Roles of Fe superoxide dismutase and catalase in resistance of Campylobacter coli to freeze-thaw stress.
نویسندگان
چکیده
We demonstrated that oxidative stress plays a role in freeze-thaw-induced killing of Campylobacter coli following analysis of mutants deficient in key antioxidant functions. Superoxide anions, but not H(2)O(2), were formed during the freeze-thaw process. However, a failure to detoxify superoxide anions may lead to spontaneous disproportionation of the radicals to H(2)O(2).
منابع مشابه
Catalase and Superoxide Dismutase in Escherichia coli ROLES IN RESISTANCE TO KILLING BY NEUTROPHILS*
We assessed the roles of intrabacterial catalase and superoxide dismutase in the resistance of Escherichia coli to killing by neutrophils. E. coli in which the synthesis of superoxide dismutase and catalase were induced by paraquat 10-fold and 5-fold, respectively, did not resist killing by neutrophils. When bacteria were allowed to recover from the toxicity of paraquat for 1 h on ice and for 3...
متن کاملGeneration of a superoxide dismutase (SOD)-deficient mutant of Campylobacter coli: evidence for the significance of SOD in Campylobacter survival and colonization.
The microaerophilic nature of Campylobacter species implies an inherent sensitivity towards oxygen and its reduction products, particularly the superoxide anion. The deleterious effects of exposure to superoxide radicals are counteracted by the activity of superoxide dismutase (SOD). We have shown previously that Campylobacter coli possesses an iron cofactored SOD. The sodB gene of C. coli UA58...
متن کاملIncreased Serum Superoxide Dismutase and Catalase Activities in Streptozotocin-Induced Diabetic Rats
Abstract Background and Objective: One of the diabetes complications is the tissue damage caused by the imbalance of oxidants and antioxidants (oxidative stress). The aim of the present study was to evaluate the activity of two antioxidant enzymes -superoxide dismutase and catalase- in the serum of streptozotocin-induced diabetic rats. Material and Methods: This investigation was conduct...
متن کاملThe antioxidant effect of hesperetin and nano-hesperetin on activity of catalase and superoxide dismutase enzymes in the hippocampus of animal model of Parkinson's disease
Background and objectives: Hesperetin flavanone is a natural bioflavonoid found abundantly in citrus fruits with antioxidant and anti-inflammatory properties. Nano sizing techniques improve the bioavailability of poorly soluble drugs such as hesperetin. Main feature of Parkinson's disease is the degeneration of dopaminergic neurons in the substantia nigra. The rate of oxidative...
متن کاملAntioxidant Effect of Lycopersicum esculentum on Plasma Superoxide Dismutase, Catalase and Malondialdehyde in Rat Espoused with Lead Acetate
Background: Lead, an example of heavy metals, has, for decades, being known for its adverse effects on various body organs and systems such that their functions are compromised. Objective: In the present study, the ability of Lycopersicum esculentum on decrease toxic effects of lead acetate on plasma superoxide dismutase, catalase and malondialdehyde in Rat. Lead to adversely affect the Liver ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Applied and environmental microbiology
دوره 66 7 شماره
صفحات -
تاریخ انتشار 2000